We believe evidence is a duty, not a chore
Our digital treatments Sleepio and Daylight aren’t just based on science: They’ve been proven effective in gold-standard clinical trials.
Setting the standard for rigorous clinical evidence
We believe digital treatments must be put to the test as rigorously as traditional medicine. People’s mental health depends on it. That belief not only fuels our commitment to clinical evidence — it also drives our efforts to make research more equitable for underserved populations.
90+
Peer-reviewed publications
18
Randomized controlled trials (RCTs)
28k+
Participants across all evidence papers
4
Sleepio references in clinical guidelines1-4

Sleepio helped 76% of patients achieve clinical improvement in insomnia
In a placebo-controlled trial, Sleepio was shown to be significantly more effective than the placebo. After six weeks, 76% of Sleepio patients achieved clinical improvement in insomnia.5

Daylight helped 71% of patients achieve clinical improvement in anxiety
In a landmark study, Daylight demonstrated significantly greater reductions in symptoms of clinical anxiety than the control condition. After 10 weeks, 71% of Daylight patients moved from clinical to non-clinical levels of anxiety, as compared to 33% of those in the control group.6
Featured studies
Improving sleep after stroke: A RCT of dCBT for insomnia
Read paperEfficacy of a dCBT for insomnia in people with low back pain
Read paperThe effects of dCBT for insomnia on cognitive function
Read paperEfficacy of dCBT for moderate-to-severe symptoms of generalized anxiety disorder
Read paperA randomized controlled trial of dCBT for insomnia in pregnant women
Read paperEfficacy of dCBT for the treatment of insomnia symptoms among pregnant women
Read paperA pilot RCT for dCBT for sub-threshold insomnia
Read paperEfficacy of dCBT for insomnia to improve depression across demographic groups
Read paperRCT on impact of dCBT for insomnia on health, wellbeing, and quality of life
Read paperThe effects of improving sleep on mental health (OASIS)
Read paperSleep to lower elevated blood pressure (SLEPT)
Read paperHelping employees sleep well: effects of CBT for insomnia on work outcomes
Read paperSleep and productivity benefits of digital CBTi
Read paperYou might also enjoy…

Landmark study reveals the effectiveness of Daylight in improving anxiety
Dr. Jenna Carl helps leading employers contextualize the results of a landmark clinical trial evaluating the safety and efficacy of…

New study finds digital CBT the most cost effective option for poor sleep, when compared to other leading choices
Digital Cognitive Behavioral Therapy (dCBT), as delivered by Sleepio, was found to be the most cost-effective intervention overcoming poor sleep.

How DTx Will Set the Standard for Evidence in Digital Health: A Presentation from DTx West
DTx might be the future of mental health care. But only if companies prioritize high-quality research above quick turnaround.
During the COVID-19 public health emergency, Sleepio and Daylight are being made available as treatments for insomnia disorder and generalized anxiety disorder (GAD), respectively, without a prescription. Sleepio and Daylight have not been cleared by the U.S. Food and Drug Administration (FDA) for the treatment of insomnia disorder and GAD, respectively.
1. Qaseem, A., Kansagara, D., Forciea, M. A., Cooke, M., & Denberg, T. D. (2016). Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 165(2), 125-133.
2. Riemann, D., Baglioni, C., Bassetti, C., Bjorvatn, B., Dolenc Groselj, L., Ellis, J. G., … & Spiegelhalder, K. (2017). European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research, 26(6), 675-700.
3. Wilson, S., Anderson, K., Baldwin, D., Dijk, D. J., Espie, A., Espie, C., … & Sharpley, A. (2019). British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: an update. Journal of Psychopharmacology, 33(8), 923-947.
4. King’s Technology Evaluation Centre. (2017, November 9). Overview: Health app: SLEEPIO for adults with poor Sleep: Advice. NICE. https://www.nice.org.uk/advice/mib129.
5. Espie, C. A., Kyle, S. D., Williams, C., Ong, J. C., Douglas, N. J., Hames, P., & Brown, J. S. (2012). A randomized, placebo-controlled trial of online cognitive behavioral therapy for chronic insomnia disorder delivered via an automated media-rich web application. Sleep, 35(6), 769-781.
6. Carl, J. R., Miller, C. B., Henry, A. L., Davis, M. L., Stott, R., Smits, J. A., … & Espie, C. A. (2020). Efficacy of digital cognitive behavioral therapy for moderate‐to‐severe symptoms of generalized anxiety disorder: A randomized controlled trial. Depression and Anxiety, 37(12), 1168-1178.
DOC-3046 Effective 11/2023